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MicroRNA targetome suggests aberrant upregulation of T cell receptor signaling pathway molecules in ATL cells. The set of 932 targets for 24 downregluated miRNAs in ATL cells versus normal CD4+ T cells (GSE31629) were imported into the Functional Annotation tool of DAVID to identify relevant KEGG pathways. The T-cell receptor (TCR) signaling pathway (hsa04660) (p = 1.31E-5) is shown. The orange nodes represent the genes theoretically upregulated in ATL cells.
