Table 2.

Accordance of the presented patient with the Yamaguchi criteria for the diagnosis of adult-onset Still’s disease

Yamaguchi criteria (require the presence of five features, with at least two being major diagnostic criteria):	Patient’s characteristics
Major Yamaguchi criteria:
1. Fever of at least 39°C lasting at least one week.	+
2. Arthralgias or arthritis lasting two weeks or longer.	–
3. Typical rash (maculopapular, nonpruritic) during febrile episodes.	+
4. Leukocytosis (10,000/μL or greater), with at least 80% granulocytes.	+
Minor Yamaguchi criteria:
1. Sore throat	–
2. Lymphadenopathy	+
3. Hepatomegaly or splenomegaly	–
4. Abnormal liver function studies	–
5. Negative antinuclear antibodies and rheumatoid factor.	+
Exclusions
1. Infection, especially sepsis and infectious mononucleosis	✓
2. Malignancies, especially lymphomas	✓
3. Rheumatic diseases known to mimic adult Still’s disease	✓