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. 2012 Sep 24;10:200. doi: 10.1186/1479-5876-10-200

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Copyright ©2012 Xue et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FoxM1 siRNA decreased migration and invasion of Caki-1 and 786-O cells, and reduced the HUVECs tube formation.A, Scratch migration assay showing that FoxM1 siRNA decreased cell migration. B, Matrigel invasion assay showing that FoxM1 siRNA-transfected cells resulted in low penetration through the Matrigel-coated membrane, compared with control cells. C, Conditioned media from FoxM1 siRNA-transfected cells were able to significantly reduce the tube formation of HUVECs compared with the medium from control cells. The experiments were repeated thrice. **, P < 0.01, relative to control.