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. 2012 Nov 7;7(11):e48958. doi: 10.1371/journal.pone.0048958

Figure 1. miR-550a is often upregulated in HCC and promotes HCC cell migration and invasion.

Figure 1

(A, B) The relative expression of mature miR-550a in 48 pairs of HCC tissues and their corresponding noncancerous liver tissues were measured using TaqMan real-time PCR and normalized to U6 snRNA. (C, D) Transwell migration and invasion assays of Huh-7 and SK-Hep1 cells stably expressing miR-550a or mock control. (E, F) Transwell migration and invasion assays of MHCC-97L and SMMC-7721 cells transfected with a miR-550a inhibitor or negative control. Representative images are shown on the left, and quantification is shown on the right. The results are representative of at least three independent experiments, and the values shown are the mean ± SD.