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. 2012 Jun 18;12:250. doi: 10.1186/1471-2407-12-250

Table 3.

Groups of tobacco-related cancer sites with mutually significantly increased risk of subsequent primary cancer valid for at least one sex and split into pairs (Bavaria; 2002–2008; for each pair, the respective identified sex is given as well as known shared risk factors; data sources,[17-21])

Group Pair of cancer types with mutually significantly elevated risk of subsequent primary cancer Sex Shared risk factors in addition to tobacco smoking
1
mouth/pharynx – oesophagus
m,f
alcohol consumption, low fruit and vegetable intake, low socioeconomic status
 
mouth/pharynx – larynx
m,f
alcohol consumption, low fruit and vegetable intake
 
mouth/pharynx – lung/bronchus
m,f
low fruit and vegetable intake
 
oesophagus – larynx
m
alcohol consumption, low fruit and vegetable intake
 
larynx – lung/bronchus
m
low fruit and vegetable intake
 
lung/bronchus – oesophagus
m
low fruit and vegetable intake
2
lung/bronchus – kidney
m,f
-
 
kidney – bladder
m,f
-
 
bladder – lung/bronchus
m,f
-
3
bladder – lung/bronchus
m,f
-
 
lung/bronchus – urinary tract
f
-
 
urinary tract – bladder
f
ionizing radiation, heavy use of phenacetin-containing analgesics
4
mouth/pharynx – colon/rectum
m
alcohol consumption, low fruit and vegetable intake
5 stomach – pancreas m,f obesity