Table 4.
EORTC QLQ-C30 mean scores (SE) at each time point
|
CR &TT at T0 |
CR at T1 |
TT at T1 |
CR at T2 |
TT at T2 |
CR at T3 |
TT at T3 |
CR at T4 |
TT at T4 |
CR at T5 |
TT at T5 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| n=121 | n=62 | n=59 | n=62 | n=59 | n=50 | n=51 | n=30 | n=36 | n=16 | n=18 | |
|
physical functioning |
83,64 |
80,08 (1,64) |
79,39 (2,03) |
80,69 (1,70) |
82,03 (2,18) |
85,44 (1,96) |
83,64 (1,97) |
84,08 (3,50) |
88,69 (1,88) |
84,89 (3,29) |
89,89 (3,19) |
|
role functioning |
68,32 |
66,93 (3,51) |
64,99 (4,22) |
75,70 (3,45) |
75,79 a (4,26) |
81,86 (4,62) |
84,65 (4,45) |
85,54 (5,73) |
94,08 (5,38) |
88,11 (9,41) |
97,49 (8,67) |
|
cognitive functioning |
84,44 |
76,10 (2,82) |
77,77 (3,02) |
80,88 (2,50) |
81,27 (2,94) |
79,92 (3,60) |
83,77 (3,40) |
81,10 (4,26) |
85,95 (3,51) |
80,27 (3,23) |
86,52 (5,67) |
|
emotional functioning |
76,65 |
75,96 (2,50) |
75,44 (2,60) |
75,56 (2,60) |
78,52 (2,74) |
76,65 (3,46) |
77,32 (2,80) |
76,65 (4,36) |
80,69 (4,14) |
77,69 (6,17) |
81,34 (4,50) |
|
social functioning |
81,40 |
78,63 (2,10) |
71,71 (3,08) |
83,86 (2,64) |
82,55 a (2,89) |
89,39 (3,25) |
84,74 (3,69) |
92,52 (6,16) |
90,50 (4,48) |
92,86 (7,41) |
89,74 (6,97) |
|
global health status |
68,11 |
67,00 (2,22) |
59,02 (2,90) |
68,52 (2,24) |
65,81 (3,09) |
72,28 (2,48) |
72,61 (3,14) |
72,28 (3,22) |
76,19 (3,78) |
74,36 (4,06) |
78,53 (5,30) |
|
fatigue |
32,32 |
42,88 a (3,11) |
45,45 a (3,83) |
36,51 (2,45) |
33,28 a (3,93) |
30,93 (3,15) |
27,21 (3,58) |
24,55 (4,86) |
18,86 (3,71) |
21,91 (6,53) |
14,96 (5,55) |
|
nausea & vomiting |
6,34 |
8,84 (3,16) |
13,31 (3,20) |
4,70 (2,77) |
7,20 (2,88) |
1,47 (3,29) |
4,67 (2,62) |
3,56 (3,30) |
−0,23 (3,55) |
2,17 (5,99) |
−2,00 (6,63) |
|
pain |
24,52 |
21,74 (3,68) |
24,21 (3,45) |
20,42 (3,39) |
21,93 (3,93) |
16,53 (4,35) |
19,18 (3,55) |
17,85 (5,34) |
15,43 (4,11) |
15,14 (7,29) |
12,02 (7,38) |
|
dyspnea |
13,22 |
17,11 (3,28) |
17,47 (2,45) |
24,15 (2,89) |
22,42 (4,08) |
18,08 (3,71) |
15,22 (3,62) |
14,33 (4,65) |
14,23 (3,97) |
19,47 (4,53) |
15,31 (5,67) |
|
insomnia |
30,85 |
29,74 (3,96) |
30,25 (4,10) |
33,59 (4,43) |
31,43 (4,67) |
28,77 (4,59) |
26,19 (4,26) |
29,74 (6,08) |
19,74 (4,74) |
32,94 (6,43) |
26,69 (9,56) |
|
loss of appetite |
11,57 |
11,01 (4,00) |
20,66 (4,36) |
8,84 (3,84) |
11,57 (3,18) |
0,46 (4,48) |
6,90 (2,86) |
11,57 a (6,19) |
1,47 (4,23) |
11,57 (8,05) |
−5,10 (5,27) |
|
obstipation |
11,85 |
14,07 (3,44) |
19,12 (4,03) |
12,94 (3,89) |
18,74 (3,55) |
14,62 (4,95) |
9,85 (3,86) |
5,18 (3,71) |
9,83 (4,34) |
7,68 (7,98) |
−2,74 a (5,24) |
|
diarrhea |
5,23 |
8,01 (2,89) |
8,26 (1,99) |
9,06 (3,41) |
9,83 (2,52) |
6,62 (2,97) |
5,90 (1,78) |
9,68 (3,48) |
1,19 (1,92) |
5,23 (0,00) |
7,32 (4,78) |
| financial difficulty | 11,29 | 15,18 (2,25) | 12,51 (2,59) | 14,57 (2,88) | 11,87 (2,24) | 15,46 (2,74) | 8,63 (2,99) | 14,63 (6,26) | 5,23 (4,22) | 15,46 (4,17) | 17,54 a (7,59) |
a Indicates more or equal to ten-point difference from previous time point.
T0: baseline, T1: last day RT, T2: 3 months post-RT, T3: 1 year post-RT, T4: 2 years post-RT, T5: 3 years post-RT.