Table 2. Prevalence of some major age-related diseases and medical therapy in offspring matched-controls and centenarians' offspring.
| Disease/Condition | Offspring matched-controls | Centenarians' Offspring | P-Value1 |
|---|---|---|---|
| Myocardial Infarction (%) | 11 | 6 | 0.28 |
| Stroke (%) | 6 | 2 | 0.22 |
| Hypertension (%) | 63 | 37 | <0.001 |
| Arrhythmia (%) | 23 | 10 | 0.006 |
| Hypercholesterolemia (%) | 47 | 40 | 0.18 |
| Diabetes (%) | 10 | 10 | 0.99 |
| Dementia (%) | 1.3 | 0.5 | 0.87 |
| Cancer (%) | 20 | 11 | 0.06 |
| Osteoporosis (%) | 26 | 19 | 0.18 |
| Osteoarthrosis (%) | 56 | 44 | 0.06 |
| Medical Therapy | |||
| Subjects taking drugs (%) | 95 | 79 | 0.001 |
| Number of drugs* | 4 (2-7) | 2 (1-4) | <0.001 |
1
adjusted for age and gender
*
results are reported as medians with interquartile ranges (25th-75th percentiles).