Table 4. Correlation coefficients between parameters of the IGF-I/insulin system in centenarians' offspring and in offspring matched-controls.

	IGF-I Bioactivity	Total IGF-I	Total IGF-II	HOMA2-B%
Centenarians' offspring
Total IGF-I	0.26b
Total IGF-II	0.12	0.12
HOMA2-B%	0.13	0.11	0.14
HOMA2-S%	-0.18a	-0.18a	-0.09	-0.48c
Offspring matched-controls
Total IGF-I	0.32a
Total IGF-II	0.01	0.05
HOMA2-B%	-0.17	0.03	0.06
HOMA2-S%	0.13	0.24a	-0.1	-0.39c

^ap<0.05

^bp=0.001

^cp<0.001