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A. Bar diagram depicts the percentage of ICOS+, CXCR5+ IL-21+Tfh cells in aged and young CD4+ T cells after activation with IL-12 for 5 days. Data is mean +/− S.E. of 10 different aged and young subjects. B. Contour plot depicts the percent of ICOS+, CXCR5+ IL-21+ Tfh cells in aged and young CD4+ T cells after activation with IL-12 for 5 days. Data is representative of 10 such experiments.
