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Energy expenditure (EE) and respiratory quotient (RQ) in ShcKO and wild-type (WT) mice housed at 12°C. Mean (±SEM) EE and RQ values collected over a 24 hour period in 3 mo (A&B), 15 mo (C&D), and 27 mo (E&F) mice. ShcKO = p66 Shc(−/−) mice, mo = months.
