Table 2. IC50 (M) values of different inhibitors of two recombinant AmAChEs*.
Inhibitor | AmAce1 | AmAce2 | Ratio of IC50 † |
BW284C51 | (4.33±0.58) × 10−9 | (2.67±0.21) × 10−9 | 1.68 |
Eserin | (1.73±0.41) × 10−5 | (1.09±0.03) × 10−6 | 15.89 |
Iso_OMPA | n/a | n/a | n/a |
Chlorpyrifos oxon | (6.12±0.25) × 10−7 | (1.53±0.19) × 10−7 | 3.99 |
DDVP | (3.53±0.15) × 10−4 | (5.03±0.40) × 10−5 | 7.01 |
Malaoxon | (9.19±0.43) × 10−6 | (3.26±0.29) × 10−6 | 2.82 |
Paraoxon | (4.58±0.11) × 10−5 | (1.01±0.04) × 10−6 | 45.4 |
Aldicarb | n/a | n/a | n/a |
Carbaryl | (1.20±0.51) × 10−3 | (3.43±0.69) × 10−7 | 3.49 × 103 |
Carbofuran | (1.69±0.24) × 10−5 | (9.02±0.19) × 10−7 | 18.78 |
Propoxur | (1.85±0.12) × 10−4 | (5.33±0.49) × 10−5 | 3.48 |
Results are reported as the mean ± SD (n = 3).
AmAce1/AmAce2.