Table 4. Carnitine metabolites of dogs after consuming control* or treatment foods for 194 days.† .
Control Food | Increased (n-3) FA Food | Increased(n-3) and (n-6)FA Food | Two-way ANOVA Analysis(P values) | |||
Number of Animals, N | 13 | 12 | 13 | Diet Main Effect | Time Main Effect | Diet by Time Main Effect |
Added Fish Oil, % | 0 | 0.6 | 1.5 | |||
Added L-carnitine, mg/kg | 0 | 300 | 300 | |||
Added Coconut and Corn Oils, Reduced Animal Fat (+,–) | – | – | + | |||
Carnitine | 0.71a | 1.22b | 1.12 | <0.10 | <0.05 | |
Deoxy-carnitine | 0.95 | 0.95 | 0.89 | <0.05 | ||
Acetyl-carnitine | 1.08 | 1.57a | 1.48a | <0.05 | <0.05 | |
Stearoyl-carnitine | 1.49 | 4.00a | 0.84 | <0.05 | <0.05 | |
Propionyl-carnitine | 1.22 | 1.58a | 1.85a | <0.05 | <0.05 | |
Succinyl-carnitine | 1.04 | 1.25a | 1.39a | <0.05 | <0.10 | |
Glutaroyl-carnitine | 1.36a | 1.62a | 1.63a | <0.05 | ||
2-methylbutyroyl-carnitine | 1.10 | 2.03a | 1.87a | <0.05 | <0.05 | |
Isovaleryl-carnitine | 0.99 | 1.71a | 1.84a | <0.05 | <0.05 | <0.05 |
Hydroxyisovaleroyl-carnitine | 0.90b | 1.01 | 1.02 |
PrescriptionDiet® k/d®, Hill’s Pet Nutrition, Inc.
Using serum values from baseline, each animal served as its own control. Data are presented relative to baseline as fold change. All data were log-transformed prior to statistical analysis.
Indicates significantly increased or decreased fold-change between the diet group shown and baseline at P<0.05.
Indicates fold-change values that are trends but missed the significant cutoff (P>0.05, P<0.10).