Table 4. Combined effect of MDM2 and p14ARF genotypes on risk of SGC.
| No. of combined risk genotypes | Controls | Cases | P a | Adjusted ORb (95% CI) | ||
| (No. = 511) | (No. = 156) | |||||
| No. | (%) | No. | (%) | |||
| 0 | 32 | (6.3) | 5 | (3.2) | 0.107 | 1.0 |
| 1 | 181 | (35.4) | 47 | (30.1) | 1.7 (0.6–4.8) | |
| 2 | 219 | (42.9) | 69 | (44.2) | 2.0 (0.8–5.5) | |
| 3 | 67 | (13.1) | 27 | (17.3) | 2.7 (1.0–7.9) | |
| 4 | 12 | (2.4) | 8 | (5.1) | 5.6 (1.5–21.0) | |
| Ptrend = 0.004 | ||||||
| 0–2 | 432 | (84.5) | 121 | (77.6) | 0.043 | 1.0 |
| 3–4 | 79 | (15.5) | 35 | (22.4) | 2.0 (1.1–2.7) | |
a
Chi-square test, compared to controls.
b
Adjusted for age, sex, race/ethnicity, and radiation exposure.