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. 2012 Nov 7;7(11):e49113. doi: 10.1371/journal.pone.0049113

Table 2. Characteristics of subjects with insomnia and hypnotic use (N = 5693).

Group No. (%)
Category
BZD 1915 (33.6)
non-BZD 2812 (49.4)
BZD and non-BZD 966 (17.0)
Half-life#
Short-acting 4465 (78.4)
Intermediate-acting 895 (15.7)
Long-acting 333 (5.8)
Dose*
Low$ 2718
Medium 2971 (52.2)
High 2722 (47.8)
Period+
Remote 3434 (60.3)
Previous 792 (13.9)
Current 1467 (25.8)

Abbreviation: BZD, benzodiazepine.

#

There were 273 patients (5.76%) switched from short-acting to intermediate-acting (N = 199) or long-acting (N = 74) and 51 patients (5.39%) switched from intermediate-acting to long-acting hypnotics.

*

Low: 7 to 30 defined daily dose (DDD) per year; medium: 31 to 90 DDD per year; high: at least 91 DDD per year.

$

Additional included subjects.

+ Current: prescription of hypnotics ended within 30 days before dementia index date; previous: prescription ended 31 to 90 days before dementia index date; remote: prescription ended 91 days or more before dementia index date.