Table 1. Data underlying the estimation of the HIV-prevalence in culture-positive TB patients in Germany, 2002 to 2009§.
2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | Overall | |
no. cult+ TB notifications | 4,965 | 4,714 | 4,372 | 4,116 | 3,773 | 3,475 | 3,163 | 3,150 | 31,728 |
no. patients in ClinSurv HIV | 7,333 | 7,766 | 8,277 | 8,657 | 8,902 | 9,264 | 9,596 | 9,840 | 15,531 |
no. patients in ClinSurv HIV under ART | 5,920 | 6,343 | 6,806 | 7,097 | 7,359 | 7,776 | 8,155 | 8,523 | n.a. |
Proportion of patients in ClinSurv under ART (%) | 81 | 82 | 82 | 82 | 83 | 84 | 85 | 87 | n.a. |
no. ART prescriptions | n.a. | n.a. | n.a. | n.a. | 11,553,109 | 11,254,315 | 11,802,210 | 12,352,169 | n.a. |
no. patients from ART prescriptions | n.a. | n.a. | n.a. | n.a. | 35,185 | 36,437 | 38,730 | 42,438 | n.a. |
Coefficient | 4.80* | 4.80* | 4.80* | 4.80* | 4.78 | 4.69 | 4.75 | 4.98 | 4.80 |
no. HIV/TB cases [95%CI] | 44 [32–59] | 42 [30–57] | 41 [29–56] | 56 [42–73] | 32 [22–45] | 26 [17]–[38] | 32 [22–45] | 25 [16]–[37] | 298 [n.a.] |
no. HIV/TB cases (extrapolated) | 212[154–284] | 202 [146–273] | 198 [142–268] | 270 [204–350] | 153 [105–216] | 122 [80–179] | 153 [105–216] | 126 [81–185] | 1,430 [n.a.] |
estimated HIV-prevalence in cult+ TB (% [95%CI]) | 4.3 [3.1–5.7] | 4.3 [3.1–5.8] | 4.5 [3.2–6.1] | 6.6 [5.0–8.5] | 4.1 [2.8–5.7] | 3.5 [2.3–5.1] | 4.8 [3.3–6.8] | 4.0 [2.6–5.9] | 4.5 [n.a.] |
data sources include national tuberculosis notification data, the ClinSurv HIV cohort, and ART prescription data by Insight Health; *average of the 2006 to 2009 coefficients; no. = number; n.d. = no data; n.a. = not applicable.