Table 3. Enrichment analysis of 350 genes that recurrently showed two types of aberrations using DAVID.
Cluster number | Enrichment score | Term | Counts | Population hits | FDR |
1 | 4.14 | Extracellular matrix | 28 | 269 | 1.5E-04 |
Secreted | 66 | 1247 | 0.005 | ||
Signal | 105 | 2333 | 0.005 | ||
Signal peptide | 105 | 2333 | 0.006 | ||
Extracellular region part | 48 | 811 | 0.047 | ||
2 | 4.08 | Skeletal system development | 34 | 281 | 1.2E-07 |
Embryonic morphogenesis | 27 | 255 | 2.6E-04 | ||
Embryonic skeletal system development | 14 | 69 | 3.7E-04 | ||
Short sequence motif:Antp-type hexapeptide | 8 | 22 | 0.004 | ||
Homeobox protein, antennapedia type, conserved site | 8 | 23 | 0.005 | ||
3 | 3.45 | Extracellular matrix | 28 | 269 | 1.5E-04 |
Trimer | 9 | 23 | 2.6E-04 | ||
Extracellular matrix | 21 | 192 | 0.001 | ||
Proteinaceous extracellular matrix | 25 | 247 | 0.001 | ||
Collagen | 9 | 31 | 0.005 |
The first five terms in the first three clusters are shown, with enrichment score. The counts and population hits are the number of genes in the gene list and background gene list, respectively, mapping to a specific term. FDR, false discovery rate.