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. 2012 Nov 7;7(11):e46327. doi: 10.1371/journal.pone.0046327

Table 4. Unadjusted and adjusted risk ratios (95% CI)a of factors associated with high score at follow-up time points in patients with late stage Parkinson and Parkinsonism's disease.

Predictor Group Outcome variable
POS-PP Core-POS PDQ-8 HADs-14b
Unadjusted Adjusted Unadjusted Adjusted Unadjusted Adjusted Unadjusted Adjusted
Baseline POS-PP 1.22 ** (1.13 to 1.31) 1.10(0.97 to 1.24) 1.12 (1.06 to 1.18) ** 0.89 (0.81 to 0.99) * 1.11 (1.05 to 1.17) ** 0.89 (0.81 to 0.99) * 1.04(0.99 to 1.10)
Baseline Core-POS 1.40 (1.23 to 1.60) ** 1.30 (1.05 to 1.60) * 1.43 (1.25 to 1.63) ** 1.52 (1.24 to 1.87) ** 1.21 (1.09 to 1.34) ** 1.52 (1.24 to 1.87) ** 1.17 (1.05 to 1.30) ** 1.10(0.97 to 1.25)
Baseline PDQ-8 1.09 (1.05to 1.13) ** 1.02 (0.97 to 1.07) 1.08 (1.05 to 1.12) ** 1.28 (1.09 to 1.51) ** 1.14 (1.08 to 1.20) ** 1.08 (1.03 to 1.14) ** 1.04 (1.01 to 1.06) * 1.01(0.98 to 1.05)
Baseline HADs-14 1.22 (1.06 to 1.40) ** 1.22 (1.02 to 1.46) * 1.24 (1.08 to 1.42) ** 1.18 (1.01 to 1.38) * 1.15 (1.01 to 1.30) * 1.18(1.01 to 1.38)* 1.27 (1.11 to 1.45) ** 1.21 (1.06 to 1.39) **
Sex Female vs Male 3.20 (1.22 o 8.35) * 5.19 (1.17 to 22.95) * 1.48(0.59 to 3.71) 1.16(0.45 to 2.97) 0.74(0.27 to 2.02)
Stage Mild bilateral disease vs Wheel Chair 0.16 (0.04 to 0.56) ** 0.18(0.02 to 1.46) 0.74(0.23 to 2.40) 0.23 (0.06 to 0.81) * 0.15(0.02 to 1.39) 3.38(0.92 to 12.39)
Severe disability vs Wheel Chair 1.16(0.38 to 3.55) 1.10(0.23 to 5.23) 1.49(0.48 to 4.62) 0.87(0.28 to 2.77) 0.98(0.20 to 4.78) 3.12(0.87 to 11.21)
a

: Risk ratios were estimated using the ordinal logistic regression models, the risk ratio indicates how much more likely people with a risk factor are to have higher score in the follow-up assessment, where 1 indicates no risk in comparison to the reference group. The factors used to construct the models are showing in columns corresponding to individual outcome variables.

b

: Sample size n = 51, the modelling of other outcome variables were based on a sample size of 61.

Statistically significant effects (p<0.05) are in bold,

*

p<0.05,

**

p<0.01.