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. 2012 Nov 7;7(11):e48613. doi: 10.1371/journal.pone.0048613

Table 5. Effect of treatment with 10 μM MG132 from 0–6 or 16–22 h of maturation on meiotic maturation at 22 h after initiation of maturation (Experiment 5).a .

MG132, 0–6 h MG132, 16–22 h No. of oocytes Nuclear status, % b
GVBD MI Ana-Telo MII
No No 91 0.9±1.2c 14.2±0.8c 0.0±2.9c 84.9±3.5c
No Yes 79 0.0±1.2c 19.1±0.8d 6.0±2.9c 74.8±3.5c
Yes No 69 0.0±1.2c 34.8±0.8e 3.2±2.9c 62.0±3.5c
Yes Yes 69 1.6±1.2c 34.7±0.8e 3.6±2.9c 60.2±3.5c
Probability of treatment effectsf
MG132, 0–6 N.S. N.S. N.S. N.S.
MG132, 16–22 N.S. N.S. N.S. N.S.
Interaction N.S. P<0.09 N.S. N.S.
a

Data are least-squares means ± SEM of values from three replicates.

b

GVBD: germinal vesicle break down; MI: metaphase I; Ana-Telo: anaphase – telophase; MII: metaphase II.

c,d,e

Values in the same column with different superscript letters are significantly different (P<0.05 or, for).

f

N.S. = non-significant (P>0.10).