Table 1. Body weight, epididymal fat mass, bladder weight and glucose levels in lean and high-fat fed obese mice, treated or not with metformin (300 mg/kg/day, 14 days).

	Lean	Lean + Metformin	Obese	Obese + Metformin
Body weight (g)	28.5±0.3 (9)	28.4±0.3 (10)	45.7±1.1*** (9)	43.7±0.9*** (10)
Epididymal fat mass (g)	0.25±0.01 (9)	0.39±0.3 (10)	1.71±0.08*** (9)	1.86±0.1*** (10)
Bladder weight (mg)	24.9±4.1 (6)	25.7±0.8 (7)	27.9±6.9 (6)	27.1±0.9 (7)
Glucose (mg/dl)	139±6.6 (9)	166±10 (5)	238±12*** (10)	162±5.2# (5)

Data represent the means ± SEM for 5–10 mice.

^***p<0.001 compared with lean group;

^#p<0.001 compared with respective obese group.