Table 1.
Patients characteristics in the 3 study subgroups and stimulation data
| Group 1 : Advanced maternalage | Group 2 : Implantation faillure | Group 3 : Implantation faillure + advanced maternal age | p value | |
|---|---|---|---|---|
| Number of patients with severe male infertility (%) | 25/28 (89 %) | 12/17 (70.5 %) | 11/15 (73 %) | NS |
| Number of attempts with severe male infertility (%) | 32/40 (80 %) | 12/20 (60 %) | 13/18 (72 %) | NS |
| Age (mean ± SD) | 38 years and 11 months ± 1 year and 11 months | 32 years and 1 months ± 2 year and 7 months | 38 years and 3 months ± 1 year and 7 months | 1 vs 2 and 2 vs 3: p < 0.0001 |
| 1 vs 3: NS | ||||
| FSH units administered per attempt (mean ± SD) | 2237.86 ± 624.94 | 2836.83 ± 2827.50 | 2805.00 ± 1011.73 | 1 vs 2: p = 0.0004 |
| 1 vs 3:p = 0.006 | ||||
| 2 vs 3: NS | ||||
| E2 serum level 36 hours before oocytes retrieval (mean ± SD) | 2013.47 ± 688.06 | 2299.82 ± 1049.85 | 1592.85 ± 689.50 | 1 vs 2: p = 0.0004 |
| 1 vs 3 and 2 vs 3:p < 0.0001 | ||||
| Number of oocytes retrieval (mean ± SD) | 8.27 ± 3.19 | 9.25 ± 2.54 | 6.29 ± 2.27 | 1 vs 2:p = 0.0005 |
| 1 vs 3 and 2 vs 3:p < 0.0001 | ||||
| Day 3 basal FSH (mean ± SD) | 6.79 ± 0.68 | 6.43 ± 3.49 | 9.94 ± 6.00 | 1 vs 2: NS |
| 1 vs 3 and 2 vs 3:p = 0.003 | ||||
| Day 3 LH (mean ± SD) | 5.72 ± 2.86 | 4.53 ± 1.35 | 4.20 ± 1.69 | 1 vs 2 vs 3: NS |
| Day 3 E2 (mean ± SD) | 38.14 ± 15.09 | 31.33 ± 12.05 | 56.50 ± 23.33 | 1 vs 2 vs 3: NS |
| Follicular fluid volume (ml)(mean ± SD) | 3.95 ± 1.95 | 3.63 ± 1.94 | 3.99 ± 2.67 | 1 vs 2 vs 3: NS |
| FSH levels in FF (IU/L)(mean ± SD) | 5.021 ± 1.75 | 5.02 ± 2.44 | 5.17 ± 2.08 | 1 vs 2 vs 3: NS |