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Changes of the %FMD, %NMD and FMD/NMD ratio before and after treatment with sitagliptin therapy. (A) Flow mediated dilation (FMD) is significantly improved after 12 weeks. (B) Nitroglycerin-mediated dilation (NMD) is not improved. (C) An improved FMD/NMD ratio implies recovery of specific endothelial dysfunction. Columns are means ± SD. *P < 0.001 vs baseline.
