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Individual frames extracted from real-time video recorded during an open surgery using a compact instrumentation built in-house. A dose of 3.33 mg/kg GE3111 was administered to adult male CD-1 mice. The compact instrumentation was positioned immediately above the mouse. Sciatic nerve fluorescence images were acquired 4 h post-IV administration of the fluorophore (a) and compared with images from a naïve mouse receiving a control/formulation excipient only (b).
