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. 2012 Oct 27;8(10):1345–1362. doi: 10.7150/ijbs.4699

Figure 3.

Figure 3

Effects of GSP on the activities of ALT and AST in serum. (A) Experimental protocols of grouping and different doses of GSP injection. Sham: mice fed standard chow diet subjected to the surgical procedures except for liver I/R, and maintained under anesthesia for an equivalent duration. IRI control: 30 minutes of ischemia followed with 1 hour reperfusion. Dotted areas represent the periods of ischemia; Black areas represent the periods of perfusion. GSP procedures: mice injected GSP intraperitoneally 10, 20, 40mg/kg/day for 3 weeks as pharmacological preconditioning. (B) ALT and AST activities in mice serum were measured at 1 hour after perfusion. (mean±SD, n=10/group). Activities of these two enzymes are significantly lower in serum in GSP-2 and GSP-3 groups. (△indicate P<0.01 when compared with sham group; *indicate P<0.01 when compared with IRI control group; #indicate P<0.05 when compared with GSP-2 group).