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Regulation of Csk. (A) Superimposed model of the six Csk molecules in an asymmetric unit. Active molecules are shown in green and inactive molecules are in blue. (B) Schematic models of active and inactive Csk structures. (B: boxes) Arrangements of the catalytically important residues in active and inactive Csk. The salt bridge between Lys-222 and Glu-236 is indicated by dotted lines.
