Skip to main content
. Author manuscript; available in PMC: 2012 Nov 8.
Published in final edited form as: Oncogene. 2009 Jul 20;28(40):3526–3536. doi: 10.1038/onc.2009.211

Figure 5.

Figure 5

The silencing of HNF1A, HNF3A, and HNF3B results in a decrease of miR-122 level. The high miR-122 expressing PLC/PRF/5 cell line was transfected with 40 nM of specific siRNA directed against HNF-1A, -3A, -3B, and -4A (siRNA, black column) vs. negative control (NC, white column). Forty eight hours after the transfection, the efficiency of the silencing was confirmed by the decreased level of respective mRNA (upper panel). As shown in the lower panel, the silencing of HNF-1A, -3A, and -3B significantly reduces the level of miR-122.