Table 1.
Clinical and pathological features of HCC cases
| Gender | # cases |
|---|---|
| Female | 16 |
| Male | 48 |
| Age | |
| Median (range) | 62 (34–85) |
| < 60 | 27 |
| > 60 | 37 |
| Survival (months) | |
| Mean ± s.e.m. | 34.8 ± 4.9 |
| Cirrhosis | |
| No | 33 |
| Yes | 31 |
| Plasma α-fetoprotein | |
| < 300 ng/mL | 41 |
| > 300 ng/mL | 23 |
| Etiology | |
| HBV | 18 |
| HCV | 13 |
| HBV + HCV | 3 |
| ALD | 13 |
| ALD + Viral infection a | 4 |
| other | 2 |
| unknown | 11 |
| Tumor size | |
| < 5 cm | 34 |
| > 5 cm | 30 |
| Edmondson-Steiner grade | |
| Grade 1 | 1 |
| Grade 2 | 26 |
| Grade 3 | 33 |
| Grade 4 | 4 |
| Vascular invasion | |
| No | 14 |
| Yes | 29 |
| Gene signatures b | |
| Good prognosis | 40 |
| Bad prognosis | 24 |
| Hepatocyte | 49 |
| Hepatoblast | 15 |
| c-Met Negative | 45 |
| c-Met positive | 19 |
| TGF-β Early | 12 |
| TGF-β Late | 14 |
a
Either HVB or HCV infection
b
From our previously published HCC stratification (Lee et al., 2004a; Kaposi-Novak et al., 2006; Lee et al., 2006; Coulouarn et al., 2008)