Figure 1.
Schematic of procedure for suspension cell infection with C. trachomatis serovar F/Cal-I-13, purification of chlamydial forms and vesicle isolation. Multiple concentrations of OptiPrep™ density gradient medium used in this study are as indicated. Abbreviations: EB, elementary body; RB, reticulate body; PF, persistent form; SPG, sucrose-phosphate-glutamate buffer; PBS, phosphate buffered saline.