Table IV.
Variable | No. of patients (%) | P-value | Hazard ratio | 95% confidence interval |
---|---|---|---|---|
Age at surgery (years) | ||||
<68 | 53 (51.5) | 0.131 | 1.502 | 0.885–2.548 |
≥68 | 50 (48.5) | |||
Gender | ||||
Male | 97 (94.2) | 0.904 | 0.939 | 0.339–2.602 |
Female | 6 (5.8) | |||
Tumor size (mm) | ||||
≤30 | 39 (37.9) | 0.031 | 1.897 | 1.059–3.396 |
>30 | 64 (62.1) | |||
Lymph node metastasis | ||||
n(−) | 70 (68.0) | <0.001 | 3.028 | 1.785–5.136 |
n(+) | 33 (32.0) | |||
Lymphatic invasion | ||||
ly(0, 1) | 84 (81.6) | <0.001 | 3.298 | 1.827–5.952 |
ly(2, 3) | 19 (18.4) | |||
Venous invasion | ||||
v(−) | 53 (51.5) | 0.145 | 1.486 | 0.873–2.530 |
v(+) | 50 (48.5) | |||
Histological differentiation | ||||
Well, moderate | 90 (87.4) | 0.036 | 2.092 | 1.050–4.168 |
Poor | 13 (12.6) | |||
Stromal type | ||||
Medullary, intermediate | 70 (68.0) | 0.465 | 1.229 | 0.706–2.139 |
Scirrhous | 33 (32.0) | |||
Infiltrating pattern | ||||
INFc(−) | 64 (62.1) | 0.003 | 2.209 | 1.301–3.749 |
INFc(+) | 39 (37.9) | |||
Budding | ||||
Bud(−) | 49 (47.6) | <0.001 | 3.276 | 1.841–5.827 |
Bud(+) | 54 (52.4) |
n(−)/n(+), lymph node metastasis-negative/positive; INFc(−)/INFc(+), INFc component-negative/positive; Bud(−)/Bud(+), budding-negative/positive.