Table 1.
Baseline patient characteristics (N = 35)
Characteristic | n | % |
Age (years) | ||
Median | 61 | |
Range | 42–81 | |
Gender | ||
Female | 4 | 11 |
Male | 31 | 89 |
ECOG performance status | ||
0 | 6 | 17 |
1 | 23 | 66 |
2 | 6 | 17 |
Location of primary tumor | ||
Esophageal | 12 | 34 |
GE junction | 8 | 23 |
Gastric | 15 | 43 |
Location of metastasesa | ||
Lymph nodes | 24 | 69 |
Liver | 20 | 57 |
Bone | 9 | 26 |
Lung | 7 | 20 |
Peritoneum | 8 | 23 |
No. of prior chemotherapy regimens | ||
1 | 9 | 26 |
2 | 26 | 74 |
Prior treatment | ||
Cisplatin/irinotecan | 14 | 40 |
5-fluorouracil/leuocovorin/oxaliplatin | 6 | 17 |
Docetaxel/cisplatin/irinotecan/bevacizumab | 6 | 17 |
Docetaxel/cisplatin/irinotecan | 4 | 11 |
Epirubicin/cisplatin/fluorouracil | 4 | 11 |
Docetaxel/bevacizumab | 4 | 11 |
Docetaxel | 3 | 9 |
Otherb |
Does not sum to 100%, as patients may have metastases to more than one location.
Other prior chemotherapy regimens include the following: epirubicin–cisplatin–capecitabine (1), epirubicin–oxaliplatin–capecitabine (2), cisplatin–docetaxel (1), cisplatin–5-fluorouracil (1), capecitabine–oxaliplatin (2), cisplatin–irinotecan–capecitabine (2), irinotecan (1), 5-fluorouracil–leucovorin–irinotecan (1), capecitabine (1), capecitabine–docetaxel (1), carboplatin–paclitaxel (1), XL880 (1), cyclophosphamide–methotrexate–celecoxib (1).
ECOG, Eastern Cooperative Oncology Group; GE, gastroesophageal.