Table 2.

Treatment-related toxicity

Toxicity	Maximum toxicity grade
	1		2		3		4
	n	%	n	%	n	%	n	%
Hematologic
Hemoglobin	9	26	7	20	1	3	–
Leukocytes	4	11	–		–		–
Lymphocytes	3	9	4	11	1	3	–
Platelets	1	3	–		–		–
Biochemical parameters
Hypomagnesemia	14	40	–		–		–
Hyperglycemia	5	14	3	9	–		–
Aspartate aminotransferase	4	11	1	3	–		–
Alanine aminotransferase	3	9	1	3
Alkaline phosphatase	2	6	3	9	–		–
Hyponatremia	4	11	–		–		–
Hypokalemia	1	3	–		–		–
Hypoalbuminemia	2	6	2	6	–		–
Bilirubin	–		1	3	–		–
Other toxic effects
Abdominal pain	4	11	2	6	–		–
Chest pain	1	3	1	3	–		–
Hypersensitivity reaction	1	3	–		–		–
Alopecia	4	11	1	3	–		–
Anorexia	6	17	8	23	–		–
Constipation	5	14	4	11	–		–
Cough	–		2	6	–
Dehydration	–		4	11	–		–
Diarrhea	5	14	2	6	–		–
Dry skin	5	14	1	3	–		–
Dyspnea	2	6	–		–		–
Fatigue	7	20	13	37	2	6	–
Fever	6	17	–		–		–
Headache	2	6	2	6	1	3	–
Mucositis	4	11	–		–		–
Nail changes	2	6	–		–		–
Nausea	10	29	2	6	1	3
Sensory neuropathy	1	3	1	3	–		–
Acneiform rash	16	46	10	29	1	3
Vomiting	5	14	3	9	–		–
Weight loss	4	11	–		–		–
Rigors/chills	1	3	1	3	–		–
Pruritis/itching	1	3	–		1	3	–