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. Author manuscript; available in PMC: 2012 Nov 8.
Published in final edited form as: J Immunol. 2011 Sep 12;187(8):4338–4346. doi: 10.4049/jimmunol.1100854

FIGURE 3.

FIGURE 3

Immunohistochemistry showing increased number of CD3+ IELs in gliadin-sensitized mice. CD3+-stained sections of the proximal small intestine in untreated controls (A), anti-CD25 mAb-treated (B), gliadin-sensitized (C), anti-CD25 mAb-treated plus BSA-sensitized (D), and anti-CD25 mAb-treated plus gliadin-sensitized mice (E). Original magnification ×40. Black arrows indicate IELs. F, Quantification of CD3+ cells in villi tips, expressed as IEL per 100 enterocytes (n = 8 for each group). Data are represented as mean ± SEM; p values were computed using an ANOVA with a post hoc test for multiple comparisons. **p < 0.01 versus control mice, anti-CD25 mAb treated mice, and anti-CD25 + BSA-treated mice.