Table 3.
Summary of Mutation Types in the gpt Gene of Male and Female gpt Delta B6C3F1 Mice 10 Weeks After Treatment With a Single 6 mg/kg Dose of AFB1
| Mutation types | AFB1 | |
|---|---|---|
| Male | Female | |
| Transition: | ||
| G:C to A:T | 11 (13) | 9 (12) |
| A:T to G:C | 0 | 0 |
| Transversion: | ||
| G:C to T:A | 58 (71) | 50 (67) |
| G:C to C:G | 6 (7) | 4 (5) |
| A:T to T:A | 3 (4) | 5 (7) |
| A:T to C:G | 0 | 0 |
| Deletion: | ||
| 1 bp | 2 (2) | 4 (5) |
| > 1 bp | 0 | 0 |
| Insertion | 2 (2) | 3 (4) |
| Total number of mutants | 55 (100) | 75 (100) |
Note. The percentage of each type of mutation is shown in parentheses.