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. 2012 Apr 20;128(2):326–333. doi: 10.1093/toxsci/kfs151

Table 6.

Summary of Mutation Types in the gam Gene of Male and Female gpt Delta B6C3F1 Mice 10 Weeks After Treatment With a Single 6 mg/kg Dose of AFB1

Mutation types AFB1 DMSOa
Male Female
Transition:
    G:C to A:T 1 (3) 1 (2) 3
    A:T to G:C 0 (0) 0 (0) 0
Transversion:
    G:C to T:A 27 (67) 40 (71) 1
    G:C to C:G 0 (0) 2 (5) 0
    A:T to T:A 0 (0) 1 (2) 1
    A:T to C:G 0 (0) 0 (0) 0
Deletion
    1 bp 11 (27) 10 (18) 8
    > 1 bp 0 (0) 0 (0) 0
Insertion 1 (3) 1 (2) 1
Total number of mutants 40 (100) 56 (100) 14

Note. The percentage of each type of mutation is shown in parentheses.

aBecause few mutants were available for analysis, data from male and female mice were combined.