FIG. 2.

Hepatic ¹⁴C and lipid levels in Scd1 wild type and null mice 120 h postdose with 30 µg/kg TCDD. (A) ¹⁴C-levels were measured in lipid extracts by liquid scintillation counting after gavage with 2 µCi ¹⁴C-oleate 4 h prior to sacrifice. Gas chromatography mass spectrometry analysis of hepatic oleate (18:1n9) (B) and monounsaturated fatty acid (C) levels (expressed in nmol/g) in Scd1 wild type and null mice 168 h after oral gavage with 30 µg/kg TCDD (Angrish et al., 2011). *p < 0.05 for TCDD compared with vehicle, **p < 0.05 for Scd1 wild type TCDD compared with Scd1 null mice TCDD. Bars represent mean ± SEM, n = 5.