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Induction of CYP2A5 and CYP2E1 by chronic ethanol feeding in WT and Nrf2 –/– mice. WT and Nrf2 –/– mice were fed an ethanol diet for 3 weeks, Western blotting analyses for CYP2E1 and CYP2A5 (A) and activities of CYP2A5 (B) and CYP2E1 (C) were measured as described in Materials and Methods section. *p < 0.05, compared with Cont group; #p < 0.05, compared with WT EtOH group. Cont, Control; EtOH, Ethanol.
