Figure 3 .

The relation of basement membrane protein expression patterns associated with endothelial cell vascular islands (arrows) to nearby vessels. “L” and “CA” indicate lymphatic and blood capillary vessels, respectively. Labeling with collagen IV (A) identifies a vascular island isolated from a nearby network of blood capillaries. Dual PECAM and Collagen IV labeling shows Collagen IV extensions (arrowheads) from isolated endothelial cells either connecting (B) or approaching (C) a nearby microvessel. Scale bars = 50 μm (A), 20 μm (B, C).