Table 1. Comparison of cGMP signaling pathway homologs and transcript abundances in S. stercoralis and C. elegans.
| C. elegans gene(s) | S. stercoralis homolog(s) | S. stercoralis transcript abundance profile | Regulation consistent with C. elegans (+, +/−, −)1 |
| Ce-gpa-2 & -3 | Ss-gpa-2 & -3 | peak in L3i | + |
| Ce-daf-11 | Ss-gcy-11 2 | peak in L3i and L3+ | + |
| Ce-tax-2 | Ss-tax-2 | peak in L3i | + |
| Ce-tax-4 | Ss-tax-4 | peak in L3i | + |
1
(+) similar, (+/−) unclear, and (−) dissimilar transcript abundance patterns.
2
Homology is by phylogenetic similarity only.