Table 3.
Mean values and standard deviations of parameters that evaluate the contours generated by the three software, before and after the manual correction, for each organ of the head and neck
| AA | MA | VA | AM | MM | VM | p value | |
|---|---|---|---|---|---|---|---|
|
CTV1 | |||||||
| DSC, (SD) |
0.68 (0.19) |
0.67 (0.17) |
0.66 (0.18) |
0.72 (0.15) |
0.76 (0.11) |
0.71 (0.09) |
# |
| Sensitivity, (SD) |
0.73 (0.23) |
0.76 (0.19) |
0.74 (0.22) |
0.79 (0.18) |
0.85 (0.10) |
0.81 (0.16) |
|
| IncI, (SD) |
0.64 (0.17) |
0.61 (0.18) |
0.60 (0.17) |
0.67 (0.13) |
0.69 (0.13) |
0.65 (0.09) |
* # |
| ΔV (%), (SD) |
14.10 (25.99) |
25.92 (21.18) |
23.28 (28.44) |
17.72 (22.19) |
24.94 (26.01) |
27.40 (32.49) |
|
| Δx (mm), (SD) |
2.62 (2.02) |
2.92 (1.76) |
2.44 (1.58) |
2.12 (1.45) |
2.70 (1.03) |
2.88 (2.42) |
|
| Δy (mm), (SD) |
2.58 (2.70) |
2.66 (2.72) |
2.86 (2.37) |
2.60 (2.47) |
2.74 (2.47) |
5.30 (3.32) |
|
| Δz (mm), (SD) |
5.40 (7.98) |
5.70 (5.65) |
5.10 (5.77) |
5.40 (7.98) |
3.60 (5.67) |
4.80 (5.02) |
|
|
CTV2 | |||||||
| DSC, (SD) |
0.84 (0.03) |
0.83 (0.03) |
0.81 (0.02) |
0.85 (0.03) |
0.84 (0.03) |
0.82 (0.03) |
|
| Sensitivity, (SD) |
0.85 (0.04) |
0.86 (0.05) |
0.85 (0.05) |
0.86 (0.04) |
0.88 (0.04) |
0.86 (0.04) |
|
| IncI, (SD) |
0.83 (0.06) |
0.81 (0.06) |
0.78 (0.05) |
0.83 (0.06) |
0.81 (0.06) |
0.78 (0.06) |
|
| ΔV (%), (SD) |
3.50 (11.31) |
7.40 (13.33) |
10.00 (12.34) |
4.45 (10.20) |
8.38 (11.57) |
10.68 (12.51) |
|
| Δx (mm), (SD) |
2.95 (2.30) |
2.85 (1.85) |
3.08 (1.81) |
2.48 (2.56) |
2.95 (1.80) |
3.38 (1.37) |
|
| Δy (mm), (SD) |
2.38 (0.69) |
3.73 (2.50) |
2.53 (1.94) |
2.23 (0.95) |
3.60 (2.54) |
2.90 (1.51) |
|
| Δz (mm), (SD) |
1.50 (1.23) |
1.50 (2.12) |
1.88 (2.25) |
1.50 (1.23) |
1.88 (1.44) |
2.63 (1.44) |
|
|
Larynx | |||||||
| DSC, (SD) |
0.86 (0.04) |
0.87 (0.01) |
0.82 (0.04) |
0.90 (0.03) |
0.89 (0.02) |
0.86 (0.05) |
|
| Sensitivity, (SD) |
0.87 (0.06) |
0.88 (0.03) |
0.85 (0.06) |
0.92 (0.04) |
0.93 (0.01) |
0.91 (0.02) |
|
| IncI, (SD) |
0.86 (0.03) |
0.85 (0.03) |
0.80 (0.05) |
0.87 (0.02) |
0.85 (0.02) |
0.82 (0.08) |
|
| ΔV (%), (SD) |
1.43 (5.92) |
3.85 (6.75) |
5.83 (9.59) |
5.15 (3.37) |
8.55 (1.93) |
11.20 (11.32) |
|
| Δx (mm), (SD) |
0.65 (0.51) |
0.38 (0.48) |
0.88 (0.48) |
0.90 (0.52) |
0.53 (0.61) |
0.50 (0.00) |
|
| Δy (mm), (SD) |
0.38 (0.25) |
0.75 (0.65) |
0.40 (0.80) |
0.38 (0.25) |
0.50 (0.58) |
0.90 (0.52) |
|
| Δz (mm), (SD) |
5.63 (3.75) |
9.75 (5.81) |
3.75 (4.50) |
0.75 (0.87) |
1.50 (1.23) |
0.75 (1.50) |
|
|
Sup. Pharynx | |||||||
| DSC, (SD) |
0.36 (0.22) |
0.35 (0.12) |
0.33 (0.13) |
0.57 (0.05) |
0.50 (0.14) |
0.52 (0.11) |
|
| Sensitivity, (SD) |
0.49 (0.38) |
0.51 (0.35) |
0.47 (0.32) |
0.74 (0.10) |
0.80 (0.11) |
0.76 (0.11) |
|
| IncI, (SD) |
0.42 (0.14) |
0.42 (0.26) |
0.40 (0.23) |
0.49 (0.13) |
0.40 (0.20) |
0.42 (0.19) |
|
| ΔV (%), (SD) |
27.70 (90.39) |
67.50 (125.10) |
57.25 (112.28) |
61.63 (48.64) |
146.60 (134.73) |
107.58 (96.01) |
|
| Δx (mm), (SD) |
1.18 (1.41) |
1.43 (1.27) |
1.73 (2.45) |
0.98 (0.95) |
0.75 (0.50) |
1.03 (0.82) |
|
| Δy (mm), (SD) |
1.88 (1.38) |
1.90 (1.04) |
3.23 (3.78) |
1.13 (0.90) |
1.48 (1.63) |
1.88 (1.74) |
|
| Δz (mm), (SD) |
6.00 (3.24) |
6.75 (3.12) |
4.88 (3.75) |
3.00 (1.73) |
4.50 (2.12) |
3.38 (3.09) |
|
|
Mid. Pharynx | |||||||
| DSC, (SD) |
0.57 (0.10) |
0.56 (0.13) |
0.43 (0.19) |
0.61 (0.09) |
0.60 (0.12) |
0.62 (0.12) |
|
| Sensitivity, (SD) |
0.52 (0.12) |
0.57 (0.17) |
0.44 (0.19) |
0.59 (0.12) |
0.68 (0.15) |
0.64 (0.13) |
° |
| IncI, (SD) |
0.65 (0.13) |
0.56 (0.12) |
0.44 (0.21) |
0.64 (0.10) |
0.55 (0.13) |
0.61 (0.11) |
* # |
| ΔV (%), (SD) |
−18.94 (18.43) |
4.62 (27.73) |
4.12 (37.64) |
−7.48 (16.77) |
27.38 (34.84) |
4.66 (9.21) |
* + |
| Δx (mm), (SD) |
0.60 (0.82) |
0.80 (0.45) |
1.20 (1.11) |
0.90 (0.82) |
0.80 (0.45) |
0.70 (0.57) |
|
| Δy (mm), (SD) |
3.32 2.64() |
2.78 (1.08) |
2.64 (2.256) |
3.02 (2.78) |
2.76 (2.32) |
1.68 (1.29) |
|
| Δz (mm), (SD) |
4.20 (4.55) |
3.90 (4.70) |
4.80 (5.13) |
4.20 (4.42) |
5.40 (4.81) |
5.10 (5.37) |
|
|
Inf. Pharynx | |||||||
| DSC, (SD) |
0.65 (0.07) |
0.66 (0.05) |
0.63 (0.07) |
0.71 (0.04) |
0.72 (0.03) |
0.72 (0.04) |
|
| Sensitivity, (SD) |
0.59 (0.08) |
0.65 (0.08) |
0.60 (0.09) |
0.67 (0.04) |
0.72 (0.10) |
0.73 (0.07) |
* |
| IncI, (SD) |
0.75 (0.11) |
0.69 (0.07) |
0.66 (0.09) |
0.75 (0.10) |
0.72 (0.05) |
0.72 (0.09) |
# ^ |
| ΔV (%), (SD) |
−20.04 (15.57) |
−5.58 (17.12) |
−7.46 (16.01) |
−9.96 (14.02) |
1.62 (19.64) |
3.22 (18.60) |
* # |
| Δx (mm), (SD) |
1.12 (0.44) |
0.72 (0.47) |
0.90 (0.65) |
0.60 (0.55) |
0.50 (0.50) |
0.70 (0.48) |
|
| Δy (mm), (SD) |
2.06 (2.28) |
1.62 (1.63) |
1.38 (1.43) |
1.90 (2.12) |
1.52 (0.61) |
1.28 (2.07) |
|
| Δz (mm), (SD) |
3.90 (3.29) |
2.70 (1.26) |
3.00 (3.82) |
4.50 (3.52) |
4.20 (2.47) |
2.70 (3.25) |
|
|
Thyroid | |||||||
| DSC, (SD) |
0.73 (0.11) |
0.77 (0.06) |
0.73 (0.07) |
0.81 (0.05) |
0.82 (0.06) |
0.82 (0.05) |
^ |
| Sensitivity, (SD) |
0.79 (0.15) |
0.81 (0.10) |
0.79 (0.08) |
0.86 (0.08) |
0.84 (0.05) |
0.84 (0.04) |
|
| IncI, (SD) |
0.69 (0.11) |
0.75 (0.10) |
0.70 (0.11) |
0.78 (0.10) |
0.81 (0.10) |
0.80 (0.07) |
° |
| ΔV (%), (SD) |
14.86 (23.01) |
10.34 (28.54) |
15.70 (26.54) |
14.00 (25.25) |
5.72 (17.65) |
5.98 (9.27) |
° |
| Δx (mm), (SD) |
0.98 (0.82) |
1.26 (1.51) |
1.48 (1.37) |
0.50 (0.00) |
0.70 (0.98) |
1.56 (1.93) |
|
| Δy (mm), (SD) |
1.18 (1.06) |
0.98 (0.90) |
1.68 (2.12) |
0.70 (0.45) |
0.40 (0.42) |
0.60 (0.55) |
|
| Δz (mm), (SD) |
3.00 (2.37) |
2.10 (2.28) |
1.50 (1.50) |
2.70 (2.47) |
1.20 (1.96) |
2.10 (1.34) |
|
|
Masticator space right | |||||||
| DSC, (SD) |
0.80 (0.04) |
0.82 (0.03) |
0.80 (0.03) |
0.85 (0.02) |
0.84 (0.04) |
0.84 (0.02) |
° |
| Sensitivity, (SD) |
0.79 (0.07) |
0.84 (0.03) |
0.80 (0.06) |
0.83 (0.07) |
0.91 (0.02) |
0.86 (0.03) |
° + = |
| IncI, (SD) |
0.84 (0.10) |
0.80 (0.03) |
0.80 (0.02) |
0.86 (0.05) |
0.79 (0.07) |
0.82 (0.02) |
+ ^ |
| ΔV (%), (SD) |
−3.52 (21.72) |
4.74 (3.43) |
−0.62 (6.99) |
−3.16 (12.28) |
16.28 (12.24) |
5.14 (2.48) |
° = |
| Δx (mm), (SD) |
0.82 (0.58) |
1.00 (0.5) |
0.82 (0.58) |
0.50 (0.71) |
0.90 (0.82) |
0.82 (0.30) |
|
| Δy (mm), (SD) |
1.12 (0.69) |
1.20 (0.99) |
1.20 (1.29) |
1.02 (0.36) |
1.78 (1.85) |
1.30 (1.19) |
|
| Δz (mm), (SD) |
3.30 (1.64) |
4.80 (5.13) |
5.40 (4.70) |
2.70 (0.67) |
3.00 (3.52) |
2.70 (1.64) |
|
|
Masticator Space left | |||||||
| DSC, (SD) |
0.79 (0.05) |
0.81 (0.05) |
0.77 (0.05) |
0.86 (0.02) |
0.86 (0.03) |
0.85 (0.02) |
* # ° |
| Sensitivity, (SD) |
0.72 (0.08) |
0.79 (0.08) |
0.73 (0.09) |
0.82 (0.05) |
0.89 (0.03) |
0.86 (0.04) |
* ° + ^ |
| IncI, (SD) |
0.89 (0.05) |
0.85 (0.01) |
0.82 (0.01) |
0.90 (0.02) |
0.83 (0.07) |
0.84 (0.03) |
° + ^ |
| ΔV (%), (SD) |
−18.64 (12.32) |
−7.02 (10.16) |
−10.58 (12.18) |
−8.30 (5.83) |
8.26 (10.51) |
3.00 (5.82) |
° + ^ |
| Δx (mm), (SD) |
0.84 (1.34) |
1.02 (0.65) |
1.02 (0.82) |
1.040 (0.96) |
0.92 (0.58) |
0.62 (0.69) |
|
| Δy (mm), (SD) |
2.26 (1.85) |
1.76 (1.27) |
2.12 (0.80) |
1.820 (1.08) |
2.52 (2.76) |
1.94 (1.37) |
|
| Δz (mm), (SD) |
3.00 (2.60) |
6.00 (5.09) |
6.00 (5.91) |
2.40 (0.82) |
3.00 (4.37) |
2.40 (1.34) |
|
|
Mandible | |||||||
| DSC, (SD) |
0.89 (0.02) |
0.86 (0.02) |
0.84 (0.02) |
0.90 (0.02) |
0.89 (0.02) |
0.89 (0.02) |
* |
| Sensitivity, (SD) |
0.87 (0.05) |
0.86 (0.04) |
0.82 (0.04) |
0.88 (0.04) |
0.92 (0.03) |
0.92 (0.03) |
+ ^ |
| IncI, (SD) |
0.92 (0.02) |
0.86 (0.05) |
0.86 (0.06) |
0.92 (0.02) |
0.86 (0.05) |
0.87 (0.05) |
* # + ^ |
| ΔV (%), (SD) |
−4.76 (7.12) |
−0.48 (9.51) |
−3.60 (12.00) |
−3.88 (6.02) |
7.06 (9.05) |
7.02 (8.78) |
|
| Δx (mm), (SD) |
0.30 (0.27) |
0.60 (0.42) |
0.50 (0.35) |
0.30 (0.27) |
0.70 (0.57) |
0.30 (0.27) |
|
| Δy (mm), (SD) |
0.30 (0.27) |
0.40 (0.22) |
0.50 (0.35) |
0.30 (0.27) |
0.30 (0.27) |
0.20 (0.27) |
|
| Δz (mm), (SD) |
0.60 (0.82) |
0.30 (0.67) |
1.20 (1.26) |
0.90 (0.82) |
0.60 (0.82) |
0.60 (0.82) |
|
|
Spinal cord | |||||||
| DSC, (SD) |
0.70 (0.10) |
0.81 (0.05) |
0.78 (0.06) |
0.84 (0.02) |
0.87 (0.01) |
0.86 (0.01) |
* |
| Sensitivity, (SD) |
0.60 (0.14) |
0.78 (0.10) |
0.75 (0.08) |
0.78 (0.05) |
0.87 (0.03) |
0.88 (0.04) |
* # |
| IncI, (SD) |
0.89 (0.07) |
0.86 (0.07) |
0.83 (0.08) |
0.91 (0.05) |
0.87 (0.02) |
0.84 (0.03) |
|
| ΔV (%), (SD) |
−32.46 (19.30) |
−9.00 (16.93) |
−8.40 (14.92) |
−13.18 (9.26) |
0.66 (4.55) |
5.52 (8.34) |
* # + ^ |
| Δx (mm), (SD) |
0.80 (0.45) |
0.60 (0.22) |
0.92 (0.66) |
1.00 (0.80) |
0.90 (0.42) |
0.30 (0.27) |
|
| Δy (mm), (SD) |
3.62 (6.98) |
4.88 (7.20) |
2.78 (3.96) |
0.92 (0.43) |
0.32 (0.72) |
0.62 (0.59) |
|
| Δz (mm), (SD) |
7.80 (11.74) |
7.20 (12.79) |
6.00 (10.92) |
0.60 (0.82) |
0.30 (0.67) |
0.00 (0.00) |
|
|
Parotid gland right | |||||||
| DSC, (SD) |
0.78 (0.08) |
0.79 (0.07) |
0.73 (0.08) |
0.80 (0.06) |
0.82 (0.05) |
0.80 (0.05) |
# ° = |
| Sensitivity, (SD) |
0.79 (0.13) |
0.82 (0.12) |
0.79 (0.16) |
0.82 (0.12) |
0.86 (0.10) |
0.84 (0.10) |
+ |
| IncI, (SD) |
0.80 (0.11) |
0.77 (0.09) |
0.71 (0.08) |
0.80 (0.09) |
0.79 (0.07) |
0.79 (0.10) |
# |
| ΔV (%), (SD) |
−1.06 (21.92) |
8.96 (21.67) |
13.02 (29.54) |
4.40 (22.94) |
10.40 (18.23) |
9.14 (23.61) |
* |
| Δx (mm), (SD) |
1.50 (1.00) |
1.62 (1.24) |
2.02 (1.06) |
1.96 (1.79) |
1.62 (1.24) |
1.94 (1.19) |
|
| Δy (mm), (SD) |
6.46 (7.06) |
5.64 (5.66) |
6.58 (6.25) |
6.4 (7.11) |
4.32 (6.34) |
5.76 (7.04) |
|
| Δz (mm), (SD) |
2.40 (0.82) |
2.40 (0.82) |
3.60 (2.51) |
1.80 (1.26) |
1.50 (1.06) |
1.20 (1.64) |
|
|
Parotid gland left | |||||||
| DSC, (SD) |
0.79 (0.07) |
0.78 (0.08) |
0.73 (0.04) |
0.80 (0.07) |
0.81 (0.06) |
0.81 (0.05) |
° |
| Sensitivity, (SD) |
0.77 (0.11) |
0.79 (0.11) |
0.77 (0.05) |
0.79 (0.11) |
0.83 (0.09) |
0.85 (0.07) |
^ |
| IncI, (SD) |
0.82 (0.07) |
0.77 (0.11) |
0.69 (0.04) |
0.82 (0.09) |
0.80 (0.11) |
0.78 (0.08) |
# |
| ΔV (%), (SD) |
−5.84 (17.41) |
4.44 (20.36) |
12.96 (4.75) |
−1.88 (21.29) |
6.54 (21.64) |
9.78 (14.61) |
* |
| Δx (mm), (SD) |
2.00 (1.46) |
2.46 (1.23) |
2.12 (1.43) |
2.12 (1.62) |
2.08 (1.46) |
3.08 (1.75) |
^ |
| Δy (mm), (SD) |
1.68 (2.21) |
2.60 (1.37) |
2.12 (1.76) |
1.38 (1.60) |
0.78 (1.21) |
1.38 (2.00) |
|
| Δz (mm), (SD) |
3.60 (2.73) |
3.30 (2.68) |
4.50 (1.50) |
2.70 (1.96) |
3.60 (2.73) |
2.70 (2.23) |
|
|
Cochlea right | |||||||
| DSC, (SD) |
0.63 (0.13) |
0.63 (0.17) |
0.46 (0.16) |
0.80 (0.03) |
0.77 (0.10) |
0.69 (0.07) |
# ° ^ |
| Sensitivity, (SD) |
0.59 (0.17) |
0.68 (0.24) |
0.42 (0.13) |
0.77 (0.09) |
0.84 (0.11) |
0.80 (0.10) |
# ° |
| IncI, (SD) |
0.71 (0.17) |
0.64 (0.23) |
0.55 (0.25) |
0.88 (0.09) |
0.72 (0.07) |
0.64 (0.14) |
# + ^ |
| ΔV (%), (SD) |
−5.28 (6.84) |
16.94 (54.41) |
−15.74 (23.04) |
−7.36 (17.40) |
17.9 (21.82) |
33.98 (49.56) |
+ |
| Δx (mm), (SD) |
0.90 (0.42) |
0.72 (0.47) |
1.28 (1.11) |
0.42 (0.24) |
0.62 (0.69) |
0.72 (0.88) |
|
| Δy (mm), (SD) |
1.38 (1.77) |
1.38 (1.20) |
1.60 (1.90) |
0.40 (0.42) |
0.30 (0.27) |
0.72 (0.30) |
|
| Δz (mm), (SD) |
0.50 (0.71) |
0.90 (0.82) |
2.40 (2.01) |
0.40 (0.65) |
0.30 (0.67) |
0.90 (0.82) |
|
|
Cochlea left | |||||||
| DSC, (SD) |
0.52 (0.16) |
0.69 (0.10) |
0.59 (0.07) |
0.78 (0.07) |
0.78 (0.04) |
0.72 (0.07) |
° |
| Sensitivity, (SD) |
0.45 (0.22) |
0.69 (0.13) |
0.58 (0.07) |
0.69 (0.09) |
0.81 (0.05) |
0.75 (0.08) |
* + |
| IncI, (SD) |
0.87 (0.10) |
0.70 (0.15) |
0.63 (0.13) |
0.92 (0.05) |
0.76 (0.09) |
0.72 (0.16) |
* # + ^ |
| ΔV (%), (SD) |
−51.04 (29.55) |
6.06 (30.04) |
−5.40 (13.70) |
−23.32 (10.44) |
10.24 (12.62) |
11.50 (34.88) |
* + ^ |
| Δx (mm), (SD) |
1.00 (0.50) |
0.60 (0.42) |
1.00 (0.71) |
0.30 (0.27) |
0.40 (0.22) |
0.50 (0.50) |
|
| Δy (mm), (SD) |
0.40 (0.42) |
0.40 (0.42) |
0.90 (0.55) |
0.60 (0.55) |
0.20 (0.45) |
1.00 (0.50) |
= |
| Δz (mm), (SD) |
0.90 (0.82) |
1.00 (1.28) |
1.00 (1.28) |
0.30 (0.67) |
1.20 (1.26) |
0.40 (0.65) |
|
|
Brain stem | |||||||
| DSC, (SD) |
0.80 (0.07) |
0.81 (0.11) |
0.77 (0.15) |
0.88 (0.02) |
0.88 (0.03) |
0.89 (0.03) |
|
| Sensitivity, (SD) |
0.74 (0.09) |
0.76 (0.17) |
0.73 (0.22) |
0.86 (0.04) |
0.86 (0.08) |
0.89 (0.03) |
|
| IncI, (SD) |
0.89 (0.06) |
0.89 (0.03) |
0.85 (0.03) |
0.90 (0.02) |
0.90 (0.03) |
0.88 (0.04) |
|
| ΔV (%), (SD) |
−17.50 (8.23) |
−14.36 (19.96) |
−13.68 (26.28) |
−4.54 (6.22) |
−4.00 (10.88) |
1.44 (1.75) |
^ |
| Δx (mm), (SD) |
0.70 (0.57) |
1.32 (0.78) |
1.12 (0.69) |
0.60 (0.22) |
0.92 (0.86) |
1.04 (1.02) |
|
| Δy (mm), (SD) |
1.40 (0.82) |
1.76 (0.80) |
1.88 (0.74) |
0.68 (0.82) |
0.90 (1.34) |
1.10 (0.67) |
|
| Δz (mm), (SD) |
2.40 (3.29) |
3.00 (3.82) |
4.20 (4.67) |
0.90 (0.82) |
0.90 (1.34) |
0.30 () |
|
|
Esophagus | |||||||
| DSC, (SD) |
0.63 (0.10) |
0.65 (0.15) |
0.64 (0.13) |
0.83 (0.05) |
0.84 (0.06) |
0.83 (0.06) |
|
| Sensitivity, (SD) |
0.57 (0.15) |
0.57 (0.19) |
0.63 (0.17) |
0.85 (0.06) |
0.87 (0.04) |
0.88 (0.02) |
|
| IncI, (SD) |
0.76 (0.12) |
0.79 (0.09) |
0.67 (0.11) |
0.82 (0.10) |
0.82 (0.11) |
0.79 (0.10) |
° |
| ΔV (%), (SD) |
−21.68 (29.94) |
−27.04 (26.22) |
−5.92 (23.75) |
5.62 (18.34) |
8.26 (18.26) |
12.04 (12.37) |
|
| Δx (mm), (SD) |
1.12 (0.42) |
1.38 (1.05) |
1.54 (0.86) |
0.60 (0.65) |
0.80 (0.57) |
1.00 (0.79) |
|
| Δy (mm), (SD) |
3.84 (5.83) |
4.54 (6.48) |
3.66 (3.77) |
0.82 (0.84) |
1.12 (0.76) |
0.72 (0.79) |
|
| Δz (mm), (SD) | 7.80 (11.64) | 7.50 (12.68) | 6.60 (10.64) | 1.50 (1.06) | 1.20 (1.26) | 1.20 (1.26) | |
For automatic segmentation: *AA vs. MA: p<0.043, #AA vs. VA: p<0.043, °MA vs. VA: p<0.043.
For automatic segmentation+ manual correction: +AM vs. MM: p<0.043, ^AM vs. VM: p<0.043, =MM vs. VM: p<0.043.
Abbreviations: CTV = Clinical target volume; SD = Standard deviation, DSC = DICE similarity coefficient, IncI = inclusiveness index, AA = Abas Automatic, MA = MiM Automatic, VA = Velocity Automatic, AM = Abas Manual Correction, MM = MiM Manual Correction, VM = Velocity Manual Correction.