Table 3. Significant median differences (MD), confidence intervals (CI) and P-values (p) for cytokine levels in active TB compared to controls and LTBI after stimulation with CFP-10 and ESAT-6.

	Active TB vs controls				Active TB vs LTBI
	CFP-10		ESAT-6		CFP-10		ESAT-6
Cytokine	MD (CI)	p	MD (CI)	p	MD (CI)	p	MD (CI)	p
IFN-γ	36 (6–216)	<0.0001	139 (12–289)	<0.0001	33(2–120)	<0.0005	29 (2–190)	0.0004
IP-10	1357(411–2076)	<0.0001	920(531–1740)	<0.0001	688(320–1618)	<0.0001	741(303–1230)	<0.0001
IL-6	182 (59–364)	0.0017	182 (59–364)	<0.0001	40 (18–194)	0.0002	125 (42–270)	0.0002
IL-2	16 (9–41)	<0.0001	22 (6–42)	<0.0001	13(7–36)	<0.0001	13 (2–29)	0.0008
TNF-α	18 (10–54)	<0.0001	31 (9–104)	<0.0001	16 (6–38)	0.0007	19 (0–85)	0.002
MIP-1β	57 (4–178)	<0.0001	91 (38–257)	<0.0001	78 (36–152)	<0.0001	93 (61–243)	<0.0001
GM-CSF	2 (0–9)	0.0002	9 (1–16)	<0.0001	1 (0–6)	0.0088	3 (0–13)	0.0062
IL-13	0 (0–9)	NS	5 (0–14)	0.0001	0 (0–9)	NS	3 (0–12)	0.0071

NS: non significant.