Table 2. Expression of profibrotic cytokines, matrix molecules and cell activation markers in the kidney after UUO.

	co	UUO	p
CTGF (fold induction)	1.00±0.17	3.13±0.75	* 0.037
TGFβ (fold induction)	1.00±0.29	123.75±32.43	* 0.004
LTBP-1 (fold induction)	1.00±0.32	11.31±0.81	* <0.001
collagen I (fold induction)	1.00±0.30	13.79±4.80	* 0.019
integrin chain β1 (fold induction)	1.00±0.16	2.44±0.33	* 0.004
fibronectin (fold induction)	1.00±0.25	7.50±1.11	* 0.001
osteopontin (fold induction)	1.00±0.15	45.87±14.06	* 0.018
fibrillin-1 (fold induction)	1.00±0.33	64.47±4.29	* <0.001
vitronectin (fold induction)	1.00±0.29	14.10±15.06	0.347
nephronectin (fold induction)	1.00±0.22	1.34±0.53	0.541
fibronectin (% area stained)	2.45±0.58	9.22±2.65	* 0.023
osteopontin (% area stained)	5.64±3.02	18.82±2.97	* <0.001
fibrillin-1 (% area stained)	5.68±0.41	36.80±2.45	* <0.001
α-sma (% area stained)	2.06±0.37	14.06±4.31	* 0.031
vimentin (% area stained)	1.83±0.16	15.84±2.07	* <0.001

Co, control kidney without ureteral ligation; UUO, kidney with ureteral ligation. α-sma, α-smooth muscle actin; data are means±sem.