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. Author manuscript; available in PMC: 2013 Aug 28.
Published in final edited form as: Circulation. 2012 Aug 1;126(9):1067–1078. doi: 10.1161/CIRCULATIONAHA.112.104489

Figure 3.

Figure 3

PVAT has BAT-like heat generating properties. (A) Evaluation of thermogenic activation within BAT as described in Methods. (B) Intravascular temperature measurement in LC and SMPG KO mice subjected to surgical removal of BAT (−BAT) or sham-operated (+BAT) and exposed to cold stimuli. Each tracing is representative of six recordings. (C) Quantification of the intravascular temperature reduction after 5 min of cold exposure for each experimental group in B. (D) Quantification of the time difference between the thresholds of the onset of intravascular temperature loss and pad temperature drop defined as “response time” (shown as “RT” in upper panels) for each experimental group. Data are shown in C and D as box plots (Whiskers: min to max). n=6.