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. 2012 Nov 8;7(11):e47264. doi: 10.1371/journal.pone.0047264

Figure 1. Relationships between the serum 25(OH)D concentration and the concentrations of PTH and bone turnover markers in males.

Figure 1

(A) PTH. There was a relatively steep decrease in the concentration of PTH up to 20 ng/mL 25(OH)D and a more gradual decrease between 20 and 40 ng/mL 25(OH)D. This relationship between the serum concentrations of 25(OH)D and PTH exhibited no plateau for serum 25(OH)D levels up to 40 ng/mL. (B–D) β-CTX, OC, and P1NP, respectively. LOESS plots show the plateau levels of bone turnover markers and the 25(OH)D level at which these plateaus are reached, corresponding to 30 ng/mL. When the serum 25(OH)D levels are lower than 30 ng/mL, the levels of the bone turnover markers begin to increase.