Figure 1. Intravascular multispectral optoacoustic tomography of gold nanoparticle-bearing macrophages in rabbit aorta.
(A) Intravascular ultrasound image and (B) optoacoustic image acquired at 700 nm of an atherosclerotic rabbit aorta injected with gold nanoparticle-bearing macrophages. The arrows indicate the locations where injection was performed. (C) The normalized spectral optoacoustic response obtained in a small section on the aorta, where injection was performed. (D) Multispectral optoacoustic tomography image corresponding to the recovered spectrum overlaid onto the intravascular ultrasound image revealing the injected regions.
Reproduced with permission from [52].