Table 2. Top 10 2-test combinations, ranked according to sum of sensitivity and specificity compared to a 120 minute global neuropsychological battery.
| Rank | Tests | Administration Time (min) | Sensitivity (95% CI)1 | Specificity (95% CI)1 | PPV (95% CI)1 | NPV (95% CI)1 | OR (95% CI) |
| 1 | STRPCOL/HVLTR-LRN | 11 | 73.0 (55.6–85.7) | 83.1 (76.3–88.2) | 50.0 (35.0–62.1) | 93.0 (87.7–96.5) | 13.3 (5.8–30.7) |
| 2 | HVLTR-LRN/PD | 13 | 73.7 (56.7–86.1) | 82.0 (75.0–87.1) | 49.1 (35.4–61.7) | 93.0 (87.5–96.4) | 12.7 (5.6–29.1) |
| 3 | PASAT/BVMTR-LRN | 15 | 63.2 (46.3–77.8) | 89.7 (84.3–93.8) | 60.0 (43.9–74.3) | 90.9 (85.4–94.8) | 15.0 (6.5–34.7) |
| 4 | PASAT/HVLTR-LRN | 15 | 73.7 (56.8–86.2) | 77.6 (70.4–83.3) | 44.4 (31.7–56.5) | 92.4 (86.6–96.2) | 9.7 (4.3–21.9) |
| 5 | PASAT/PND | 8 | 71.1 (54.3–84.2) | 79.5 (72.6–85.4) | 45.8 (32.8–58.8) | 91.9 (86.0–95.6) | 9.5 (4.3–21.2) |
| 6 | HVLTR-LRN/PND | 13 | 71.1 (54.1–83.9) | 77.6 (70.4–83.3) | 42.9 (30.0–55.1) | 91.9 (86.2–95.7) | 8.5 (3.9–18.8) |
| 7 | STRPCOL/BVMTR-LRN | 11 | 54.1 (37.1–69.7) | 94.4 (89.7–97.4) | 69.0 (50.0–84.2) | 89.9 (84.5–93.9) | 19.7 (7.8–50.2) |
| 8 | STRPCOL/PD | 4 | 56.8 (40.0–71.8) | 90.6 (85.2–94.4) | 58.3 (40.7–73.7) | 90.1 (84.5–94.0) | 12.7 (5.5–29.4) |
| 9 | STRPINC/HVLTR-LRN | 11 | 64.9 (47.2–79.3) | 82.5 (75.4–87.6) | 46.2 (31.8–59.6) | 91.0 (85.4–95.0) | 8.7 (4.0–19.1) |
| 10 | PASAT/WCST | 20 | 60.0 (41.7–75.0) | 86.9 (81.0–91.7) | 51.2 (35.3–66.7) | 90.5 (84.8–94.6) | 10.0 (4.4–22.7) |
1
95% bootstrap CI for Sensitivity, Specificity, PPV and NPV.
Abbreviations: BVMTR-LRN, Brief Visuospatial Memory Test-Revised (Learning Trials); CI, Confidence Interval; HVLTR-LRN, Hopkins Verbal Learning Test-Revised (Learning Trials); NPV, Negative Predictive Value; OR, Odds Ratio; PASAT, Paced Auditory Serial Addition Test; PD, Grooved Pegboard-Dominant hand; PND, Grooved Pegboard-non Dominant hand; PPV, Positive Predictive Value; STRPCOL, Stroop Color Test; STRPINC, Stroop Incongruent Test; WCST, Wisconsin Card Sorting Test (Total Errors).