Table 3. Top 10 3-test combinations, ranked according to sum of sensitivity and specificity compared to a 120 minute global neuropsychological battery.
| Rank | Tests | Admin. Time (min) | Sensitivity (95% CI)1 | Specificity (95% CI)1 | PPV (95% CI)1 | NPV (95% CI)1 | OR (95% CI) |
| 1 | STRPCOL/PASAT/HVLTR-LRN | 16 | 86.5 (71.4–95.1) | 75.5 (67.9–81.6) | 45.7 (33.8–57.0) | 95.9 (90.7–98.4) | 19.7 (7.2–54.2) |
| 2 | TMTA/PASAT/HVLTR-LRN | 16 | 84.2 (69.4–93.9) | 76.3 (69.0–82.2) | 46.4 (33.9–58.0) | 95.2 (90.4–98.3) | 17.2 (6.7–44.2) |
| 3 | SYMS/PASAT/HVLTR-LRN | 18 | 78.9 (62.8–90.3) | 79.5 (72.4–85.0) | 48.4 (35.2–60.3) | 93.9 (88.5–97.1) | 14.5 (6.1–34.7) |
| 4 | ACTF/STRPCOL/HVLTR-LRN | 13 | 78.4 (61.9–89.7) | 80.0 (72.6–85.4) | 47.5 (34.4–59.7) | 94.1 (89.0–97.2) | 14.5 (6.1–34.7) |
| 5 | PASAT/BVMTR-LRN/PND | 18 | 76.3 (60.0–88.2) | 82.1 (75.6–87.7) | 50.9 (37.8–64.1) | 93.4 (88.0–96.9) | 14.7 (6.3–34.5) |
| 6 | PASAT/HVLTR-LRN/PD | 18 | 81.6 (65.5–91.9) | 75.6 (68.1–81.6) | 44.9 (32.9–56.3) | 94.4 (89.1–97.6) | 13.8 (5.6–33.8) |
| 7 | STRPCOL/HVLTR-LRN/PD | 14 | 78.4 (61.8–89.7) | 78.8 (71.4–84.5) | 46.0 (33.3–58.1) | 94.0 (88.7–97.1) | 13.4 (5.6–32.1) |
| 8 | TMTA/PASAT/PND | 9 | 76.3 (60.0–88.2) | 80.1 (73.5–85.9) | 48.3 (35.5–61.3) | 93.3 (87.8–96.8) | 13.0 (5.6–30.2) |
| 9 | ANIMF/STRPCOL/HVLTR-LRN | 13 | 75.7 (59.1–87.5) | 80.6 (73.6–86.0) | 47.5 (34.0–60.0) | 93.5 (88.0–96.9) | 12.9 (5.5–30.2) |
| 10 | FAS/STRPCOL/BVMTR-LRN | 17 | 64.9 (47.4–78.8) | 91.3 (85.9–95.1) | 63.2 (46.2–77.8) | 91.8 (86.6–95.5) | 19.3 (8.1–45.9) |
1
95% bootstrap CI for Sensitivity, Specificity, PPV and NPV.
Abbreviations: ACTF, Action Fluency; ANIMF, Animal Fluency; BVMTR-LRN, Brief Visuospatial Memory Test-Revised (Learning Trials); CI, Confidence Interval; FAS; Letter Fluency; HVLTR-LRN, Hopkins Verbal Learning Test-Revised (Learning Trials); NPV, Negative Predictive Value; OR, Odds Ratio; PASAT, Paced Auditory Serial Addition Test; PD, Grooved Pegboard-Dominant hand; PND, Grooved Pegboard -non Dominant hand; PPV, Positive Predictive Value; STRPCOL, Stroop Color Test; SYMS, WAIS-III Symbol Search; TMTA, Trail Making Test-A.