Table 5. Top 10 testing combinations, ranked according to sum of sensitivity and specificity compared to a 120 minute global neuropsychological battery, that take 10 minutes or less to administer.
| Rank | Tests | Admin. Time (min) | Sensitivity (95% CI)1 | Specificity (95% CI)1 | PPV (95% CI)1 | NPV (95% CI)1 | OR (95% CI) |
| 1 | TMTA/PASAT/PND | 9 | 76.3 (60.0–88.2) | 80.1 (73.5–85.9) | 48.3 (35.5–61.3) | 93.3 (87.8–96.8) | 13.0 (5.6–30.2) |
| 2 | ACTF/STRPCOL/PD/PND | 9 | 70.3 (53.3–83.3) | 88.1 (82.5–92.6) | 57.8 (42.6–72.0) | 92.8 (87.7–96.2) | 17.5 (7.5–41.1) |
| 3 | STRPCOL/PASAT/PND | 9 | 75.7 (58.6–87.8) | 78.1 (71.2–84.2) | 45.2 (32.8–58.2) | 93.1 (87.4–96.7) | 11.1 (4.8–25.7) |
| 4 | ACTF/STRPCOL/DSYM/PD | 9 | 59.5 (42.1–74.5) | 94.3 (89.4–97.3) | 71.0 (52.0–85.2) | 90.8 (85.4–94.6) | 24.1 (9.4–61.7) |
| 5 | ACTF/STRPCOL/TMTA/PND | 7 | 62.2 (45.0–76.9) | 91.3 (86.0–94.9) | 62.2 (45.2–76.9) | 91.3 (86.0–95.0) | 17.1 (7.2–40.5) |
| 6 | STRPCOL/STRPINC/PASAT/PND | 10 | 67.6 (50.0–81.5) | 85.8 (79.5–90.7) | 53.2 (38.1–67.4) | 91.7 (86.2–95.6) | 12.6 (5.5–28.7) |
| 7 | STRPCOL/TMTA/PASAT/PND | 10 | 67.6 (50.0–81.6) | 85.8 (79.7–90.7) | 53.2 (38.1–67.4) | 91.7 (86.2–95.6) | 12.6 (5.5–28.7) |
| 8 | ACTF/PASAT/PND | 10 | 76.3 (59.5–88.1) | 76.9 (69.9–83.1) | 44.6 (32.4–56.9) | 93.0 (87.3–96.7) | 10.7 (4.7–24.8) |
| 9 | ACTF/STRPCOL/PND | 6 | 70.3 (54.1–83.8) | 82.5 (76.0–87.9) | 48.1 (34.5–62.1) | 92.3 (86.9–95.9) | 11.1 (4.9–25.2) |
| 10 | STRPINC/TMTA/PASAT/PND | 10 | 67.6 (50.0–81.6) | 85.2 (78.7–90.2) | 52.1 (37.3–66.7) | 91.7 (86.2–95.5) | 12.0 (5.3–27.1) |
1
95% bootstrap CI for Sensitivity, Specificity, PPV and NPV.
Abbreviations: ACTF, Action Fluency; CI, Confidence Interval; FAS, Letter Fluency; NPV, Negative Predictive Value; OR, Odds Ratio; PASAT, Paced Auditory Serial Addition Test; PD, Grooved Pegboard-Dominant hand; PND, Grooved Pegboard -non Dominant hand; PPV, Positive Predictive Value; STRPCOL, Stroop Color Test; STROOPINC, Stroop Incongruent Test; TMTA, Trail Making Test-A.