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. 2012 Nov 8;7(11):e47366. doi: 10.1371/journal.pone.0047366

Table 1. ChIP-Seq identified GBX2 targets.

Candidate Gene ID P value Fold enrichment Number of tags Consensus motif Entrez ID
NFE2L2 2.6×10−270 26.18 376 yes 4780
EEF1A1 1.2×10−36 6.26 154 yes 1915
OTUD7B 4.1×10−13 90.17 8 yes 56957
ULK4 1.2×10−12 80.17 8 yes 54986
OR5H1 3.0×10−10 12.72 19 yes 26341
ACSL1 2.9×10−9 45.09 6 no 2180
ELMO1 2.4×10−9 42.87 7 no 9844
SOCS4 9.7×10−8 45.09 5 yes 122809
PPP3CB 8.9×10−8 18.52 9 yes 5532
LAMA2 6.2×10−8 51.67 5 no 3908
PLXNA4 4.3×10−8 33.07 6 no 91584
ROBO1 3.7×10−8 56.36 5 yes 6091
SCFD2 3.7×10−8 56.36 5 yes 152579
TNFRSF21 3.7×10−8 56.36 5 no 27242
ERC2 3.7×10−8 56.36 5 yes 26059
TGFA 3.7×10−8 45.09 5 yes 7039
GUSBL1 3.5×10−8 39.68 6 yes 387036
VCL 2.1×10−8 24.8 7 yes 7414
SYT2 1.7×10−8 27.56 7 no 127833
RTN1 9.2×10−7 15.34 8 yes 6252
PARD3 9.0×10−7 12.02 10 yes 56288
FGF12 8.2×10−7 13.23 9 yes 2257
NRP1 5.3×10−7 15.03 7 yes 8829
BRE 1.9×10−7 45.09 5 yes 9577
SBF2 1.8×10−7 45.09 5 no 81846
IL1RAP 1.2×10−7 45.09 5 no 3556
MYST4 1.1×10−7 22.05 7 yes 23522
NOTCH2 9.1×10−6 14.7 6 yes 4853
PCDH15 7.3×10−6 19.84 5 yes 65217
GRIA1 5.3×10−6 8.27 9 yes 2890
USH2A 3.6×10−6 13.78 6 yes 7399
KCNB2 2.5×10−6 15.31 7 yes 9312
SLIT3 1.4×10−6 21.2 6 no 6586
TBC1D5 1.2×10−6 2.98 82 yes 9779

Genes targeted by GBX2 in human PC-3 cells based on ChIP-Seq fragments aligned to the hg18 build of the human genome on the UCSC Human Genome Browser. Bold text indicates GBX2 targets expressed in the nervous system.