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. 2012 Nov 8;7(11):e48937. doi: 10.1371/journal.pone.0048937

Figure 2. Metastin and GPR54 protein expressions in early-onset and late-onset preeclamptic placenta.

Figure 2

(A) Representative western blot of metastin and GPR54 expressions in placenta of patients with ePE and lPE compared with the matched controls. Thirty micrograms of total protein was separated on 10% SDS-PAGE gel. β-actin was used as a loading control. (B) Densitometric analysis of metastin protein expressions of placenta samples after normalization to β-actin. Metastin protein was significantly increased in early-onset preeclamptic placenta. The late-onset preeclamptic placenta revealed no significant change in expression of metastin compared with the matched control. (C) Densitometric analysis of GPR54 expression in placenta of ePE and lPE compared with their matched controls. Neither the early-onset preeclamptic placenta nor the late-onset preeclamptic placenta revealed a significant change in expression of GPR54 compared with their respective controls. Data represent means±SD after normalization to β-actin. *P<0.05, significantly decreased/increased compared with the respective control.