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. 2012 Oct 25;6(10):e1874. doi: 10.1371/journal.pntd.0001874

Figure 2. Cross-species cytokine responses to crude leishmania antigens.

Figure 2

Box plots (Tukey) for (A) IFN-γ, (B) TNF-α and (C) IL-10 responses in peripheral whole blood cells from active VL patients (n = 8) in response to SLA (an Indian L. donovani strain, 10 µg/mL), LV9 (Ethiopian L. donovani strain, 10 µg/mL), LV39 (L. major strain, 10 µg/mL). Antigen-stimulated cytokine responses are provided after subtraction of the non-stimulated control wells. Statistical differences between groups determined using the non-parametric Man-Whitney test are indicated by bars above columns, * indicates p<0.05, ** p<0.01, and *** p<0.001.