Table 5.

Factors associated with level of HCV viremia among HIV-infected women at baseline WIHS visit, multivariate ordinal logistic regression analyses using log HCV RNA level >0 to <5.0 as reference level^a

	No. of participants by HCV RNA Level (log10 copies/ml)			HCV RNA Level (log10 copies/ml)
				5.0–7.0		>7.0
Variable	>0–4.99	5.0–7.0	>7.0	OR (95% CI)b	p-Valuec	OR (95% CI)	P-Value
Age (years)
<35	22	128	8	1.0		1.0
≥35	39	473	53	2.2 (1.1–4.2)	0.02	3.5 (1.2–9.7)	0.02
Race
White	15	98	12	1.0		1.0
Hispanic	9	109	8	1.6 (0.6–4.3)	0.31	0.7 (0.2–2.9)	0.67
Black	35	386	39	1.4 (0.7–3.0)	0.39	0.7 (0.2–2.0)	0.50
Others	2	8	2	0.5 (0.1–3.1)	0.46	0.9 (0.1–8.6)	0.91
History of amphetamine use
No	53	585	59	1.0		1.0
Yes	8	15	1	0.2 (0.0–0.5)	0.002	0.7 (0.0–0.7)	0.03
History of marijuana/hash use
No	46	433	38	1.0		1.0
Yes	15	166	21	1.3 (0.6–2.9)	0.45	2.6 (1.0–6.9)	0.06
Ever had sex for drugs, money, shelter
No	25	239	32	1.0		1.0
Yes	36	361	28	0.9 (0.5–1.7)	0.73	0.5 (0.2–1.1)	0.10
Sex with injection drug user
No	22	133	17	1.0		1.0
Yes	38	458	43	2.1 (1.1–4.0)	0.03	1.4 (0.6–3.3)	0.51
Alcohol use
0/wk	30	262	28	1.0		1.0
<3/wk	16	126	10	0.9 (0.4–1.9)	0.81	0.5 (0.2–1.5)	0.23
3–13/wk	9	103	15	1.1 (0.4–2.6)	0.86	1.4 (0.5–4.5)	0.52
13+/wk	5	93	6	1.9 (0.6–5.6)	0.27	0.8 (0.2–3.7)	0.78
Current smoking
No	20	122	13	1.0		1.0
Yes	41	478	47	1.7 (0.9–3.4)	0.11	1.9 (0.7–4.9)	0.21
AIDS
No	31	400	20	1.0		1.0
Yes	30	201	41	0.5 (0.2–0.9)	0.02	2.1 (0.9–5.3)	0.10
HIV therapy
None	20	243	16	1.0		1.0
Mono	19	198	23	1.1 (0.5–2.5)	0.74	0.9 (0.3–2.8)	0.91
Combo	16	144	17	0.9 (0.4–2.2)	0.83	1.3 (0.4–4.1)	0.70
HAART	6	14	5	0.3 (0.1–1.0)	0.05	2.4 (0.5–12.3)	0.29
HIV plasma RNA (copies/ml)
<4,000	19	175	15	1.0		1.0
4,000–20,000	9	136	10	1.4 (0.5–3.4)	0.50	0.7 (0.2–2.6)	0.64
20,000–100,000	15	141	11	0.9 (0.4–2.1)	0.79	0.7 (0.2–2.4)	0.55
>100,000	17	146	25	0.7 (0.3–1.9)	0.52	1.1 (0.3–4.0)	0.86
CD4 counts(cells/ml)
>500	19	164	12	1.0		1.0
200–500	24	267	28	1.4 (0.6–3.2)	0.40	1.7 (0.6–5.2)	0.33
<200	16	158	17	1.8 (0.6–5.6)	0.29	1.7 (0.4–8.0)	0.48
CD8 counts(cells/ml)
>1200	10	114	15	1.0		1.0
800–1200	16	168	18	1.0 (0.4–2.5)	0.97	0.9 (0.3–2.9)	0.89
<800	33	307	24	0.7 (0.3–1.7)	0.41	0.3 (0.1–0.8)	0.02

^aModel includes all variables with P < 0.20 on univariate analysis

^bOdds ratio (95% confidence interval) from dichotomous logistic regression

^cP-values < 0.05 are bolded